EVALUATION OF DIFFERENT SUSPICION INDICES IN IDENTIFYING PATIENTS WITH NIEMANN-PICK DISEASE TYPE C IN CLINICAL PRACTICE: A POST HOC ANALYSIS OF A RETROSPECTIVE CHART REVIEW

Abstract Background Niemann-Pick disease Type C (NP-C) is a lysosomal lipid storage disorder with varying symptomatology depending on the age of onset.The diagnosis of NP-C is challenging due to heterogeneous nonspecific clinical presentation of the disease.NP-C Suspicion Index (SI) was developed to aid screening and identification of patients with

In this paper, we seek to present the first holistic and frugal business model ever designed to bridge the digital divide in Greenfield Africa.Based on an extensive implication in the Connecting Africa and OLPC Projects, Airtel Telecom Group (a Canadian company) partners decided to go one step further in their quest to revamp state Window Cleaners

The rapid expansion of oil and natural gas development across the Northern Great Plains has contributed to habitat fragmentation, which may facilitate brood parasitism of ground-nesting grassland songbird nests by brown-headed cowbirds (Molothrus ater), an obligate brood parasite, through the introduction of perches and anthropogenic edges.We teste

Ultra-high-performance concrete (UHPC) has been introduced for reinforced concrete structures due to its enhanced mechanical performance, including high compressive strength and tensile capacity.In certain applications, such as closure joints, connections, and concrete repairs, reinforcing steel may be embedded in dissimilar concrete elements parti